JCHOR
Journal of Current Hematology & Oncology Research

The Journal of Current Hematology & Oncology Research regularly publishes internationally qualified research in hematology and oncology within the current scholarly knowledge.

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Acquired amegakaryocytic thrombocytopenia: a diagnostic pitfall in refractory thrombocytopenia
Abstract
Acquired amegakaryocytic thrombocytopenia (AAT) is a rare hematologic disorder characterized by severe isolated thrombocytopenia caused by a selective reduction or complete absence of bone marrow megakaryocytes while other hematopoietic lineages remain relatively preserved. Because its initial clinical presentation frequently overlaps with immune thrombocytopenia (ITP), delayed diagnosis and prolonged exposure to ineffective ITP-directed therapies are common in clinical practice.

Keywords : Acquired amegakaryocytic thrombocytopenia, immune thrombocytopenia, refractory thrombocytopenia, haploidentical transplantation, bone marrow failure

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<p>Written informed consent was obtained from the patient for the publication of this correspondence and any related clinical details.</p>

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<p>The author is solely responsible for the conception, data collection, analysis, and writing of this manuscript.</p>

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Article available in :
Volume 4, Issue 4, 2026
Page : 166-167
https://doi.org/10.51271/JCHOR-0102
Article Information
Received : 14 Tem 2026
Accepted : 24 Ağu 2026
Published : 13 Kas 2026
Corresponding Author :

Serkan Güven: Department of Hematology, Çanakkale State Hospital, Çanakkale, Turkiye

[email protected]
Citation : Güven S. Acquired amegakaryocytic thrombocytopenia: a diagnostic pitfall in refractory thrombocytopenia. J Curr Hematol Oncol Res. 2026;4(4):166-167. doi:10.51271/JCHOR-0102

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