JCHOR

The Journal of Current Hematology & Oncology Research regularly publishes internationally qualified research in hematology and oncology within the current scholarly knowledge. This journal is indexed by indices that are considered international scientific journal indices (DRJI, ESJI, OAJI, etc.). According to the current Associate Professorship criteria, it is within the scope of International Article 1-d. Each article published in this journal corresponds to 5 points.

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Index
Case Report
Kikuchi-Fujimoto disease: a rare cause of fever and lymphadenopathy in a 19-year-old male
Kikuchi-Fujimoto disease is also known as histiocytic necrotizing lymphadenitis or Kikuchi disease. The disease is a rare, self-limiting condition of an undetermined cause that manifests as protracted lymphadenopathy with or without systemic symptoms. Painful cervical lymphadenopathy accompanied by fevers, leukopenia, and an increased erythrocyte sedimentation rate are its defining features. We reported a 19-year-old male was admitted to the hematology outpatient clinic with cervical lymphadenopathy and B symptoms. He was diagnosed with Kikuchi disease from a lymph node biopsy. He was successfully treated with intravenous immunoglobulin and steroids. The patient's complaints regressed and disappeared. Histopathological features, including lymph node necrosis and histiocytic growth, are used to diagnose Kikuchi-Fujimoto disease. It is regarded as a benign condition. To avoid incorrect diagnoses and needless treatments, medical professionals must be aware of Kikuchi disease while making a differential diagnosis for cervical lymphadenopathy.


1. Mahajan VK, Sharma V, Sharma N, Rani R. Kikuchi-Fujimoto disease: a comprehensive review. <em>World J Clin Cases</em>. 2023;11(16):3664-3679.
2. Payne J, Evans M, Gerrard M. Kikuchi-Fujimoto disease: a rare but important cause of lymphadenopathy. <em>Acta Paediatrica</em>. 2003;92(2):261-264.
3. Kucukardali Y, Solmazgul E, Kunter E, Oncul O, Yildirim S, Kaplan M. Kikuchi-Fujimoto disease: analysis of 244 cases. <em>Clin Rheumatol</em>. 2007; 26:50-54.
4. Dorfman R, Berry G, editors. Kikuchi&rsquo;s histiocytic necrotizing lymphadenitis: an analysis of 108 cases with emphasis on differential diagnosis. <em>Semin Diagn Pathol</em>. 1988;5(4):329-345.
5. Kuo T-t. Cutaneous Manifestation of Kikuchi&rsquo;s: histiocytic necrotizing lymphadenitis. <em>Am J Surg Pathol</em>. 1990;14(9):872-876.
6. Altuntas F, Sari I, Canoz O, et al. Kikuchi-Fujimoto disease: a rare but important cause of fever and lymphadenopathy in pregnant women. <em>Am J Hematol</em>. 2006;81(2):118-120.
7. Lin SH, Ko WS, Lee HS, Hwang WS. Kikuchi&rsquo;s disease is associated with lupus-like syndrome--a fatal case. <em>J Rheumatol</em>. 1992;19(12):1995-1996.
8. Yoshino T, Mannami T, Ichimura K, et al. Two cases of histiocytic necrotizing lymphadenitis (Kikuchi-Fujimoto&rsquo;s disease) following diffuse large B-cell lymphoma. <em>Human Pathol</em>. 2000;31(10):1328-1331.
9. Chen YH, Lan JL. Kikuchi disease in systemic lupus erythematosus: clinical features and literature review.<em>J Microbiol Immunol Infect</em>. 1998;31(3):187-192.
10. St&eacute;phan JL, Jeanno&euml;l P, Chanoz J, Gentil-P&euml;rret A. Epstein-Barr virus-associated Kikuchi disease in two children.<em>J Pediatr Hematol Oncol</em>. 2001; 23(4):240-243.
11. Cousin F, Gr&eacute;zard P, Roth B, Balme B, Gr&eacute;goire-Bardel M, Perrot H. Kikuchi disease associated with Still disease. <em>Int J Dermatol</em>. 1999;38(6):464-473.
12. Noursadeghi M, Aqel N, Gibson P, Pasvol G. Successful treatment of severe Kikuchi&rsquo;s disease with intravenous immunoglobulin. <em>Rheumatology.</em> 2006; 45(2):235-237.
13. Lin D, Villegas M, Tan P, Wang S, Shek L. Severe Kikuchi&rsquo;s disease responsive to immune modulation. <em>Singapore Med J.</em> 2010;51(1):e18-21.
14. Jang YJ, Park KH, Seok HJ. Management of Kikuchi&rsquo;s disease using glucocorticoid. <em>Laryngol Otol</em>. 2000;114(9):709-711.
Volume 2, Issue 4, 2024
Page : 95-97
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